MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino acid mitochondrial-derived peptide (MDP) encoded by the mitochondrial genome. It plays a key role in regulating metabolic homeostasis, cellular energy production, and stress response.

Product Specifications:

• Quantity: 10mg lyophilized powder per vial
• Sequence: MRWQEMGYIFYPRKLR
• Purity: High-purity research grade (>98% typically via HPLC)
• Form: Sterile, lyophilized vial for reconstitution in bacteriostatic water (research use only)
• CAS Number: 1627580-64-6

Research Applications & Potential Areas of Study

MOTS-C is widely studied for its ability to act as an exercise mimetic and metabolic regulator. Key research highlights include:

• Metabolic Health: Promotes improved insulin sensitivity, glucose uptake in skeletal muscle, and fatty acid oxidation. It has shown potential in models of insulin resistance, obesity, and type 2 diabetes.
• Exercise Performance & Endurance: Enhances physical capacity, metabolic flexibility, and muscle homeostasis. Studies in aged models demonstrate significant improvements in running endurance and energy utilization.
• Anti-Aging & Cellular Health: Supports mitochondrial function, reduces oxidative stress, and may help counteract age-related metabolic decline. Endogenous levels naturally decrease with age.
• Additional Areas: Ongoing research explores effects on inflammation, bone metabolism, neuroprotection, and overall longevity pathways (e.g., AMPK activation and mTOR modulation).

For Research Use Only. Not for human consumption, diagnostic, or therapeutic purposes. MOTS-C is intended strictly for laboratory and scientific investigation.

This peptide is supplied by Apexin Research for qualified researchers and institutions. All products undergo rigorous quality testing to ensure consistency and purity.

Ideal for studies involving metabolic syndrome, mitochondrial biology, exercise physiology, and aging research. Reconstitution and handling should follow standard peptide laboratory protocols.

Storage: Lyophilized vials stable at room temperature; refrigerate after reconstitution.